Publications

Han SY, Gai W, Yancovitz M, Osman I, Di Como CJ, Polsky D. Nucleofection is a highly effective gene transfer technique for human melanoma cell lines. Exp Dermatol. 2008 May;17(5):405-11. Epub 2008 Feb 27.(PMID: 18312380)

Abbasi NR, Yancovitz, M,; Gutkowicz-Krusin D,; Panageas KS, Mihm MC Googe P, King R, Prieto V, Osman I, Friedman R J, Rigel DS,; Kopf AW, Polsky D. "Utility of lesion diameter in the clinical diagnosis of cutaneous melanoma". Archives of dermatology. 2008; 144: 469 (PMID: 18427040)

Freedberg DE, Rigas SH, Russak J, Gai W, Kaplow M, Osman I, Turner F, Randerson-Moor JA, Houghton A, Busam K, Timothy Bishop D, Bastian BC, Newton-Bishop JA, Polsky D. Frequent p16-independent inactivation of p14ARF in human melanoma. Journal of the National Cancer Institute. 2008; 100(11):784-795 2008 Jun 4;100(11):784-95. J Natl Cancer Inst. 2008 Jun 4;100(11):784-95. Epub 2008 May 27. (PMID: 18505964)

Ng B, Zakrzewski J, Warycha M, Christos PJ, Shapiro RL, Berman RS, Pavlick AC, Polsky D, Mazumdar M, Montgomery A, Liebes L, Brooks PC, and Osman I. Shedding of distinct cryptic collagen epitope (HU177) in sera of melanoma patients. Clinical Cancer Research. 2008; Oct 1.

Doudican N, Rodriguez A, Osman I, Orlow SJ. Mebendazole induces apoptosis via Bcl-2 inactivation in chemoresistant melanoma cells. Mol Cancer Res.2008; 6(8):1308–15. Epub 2008 Jul 30. (PMID: 18667591)

O'Reilly K, Warycha M, Davies M, Zhou X, Yee H, Bhardwaj N, Pavlick A, Mills G, Rosen N, and Osman I. “4EBP1: A Node of Pathway Crosstalk in Metastatic Melanoma [abstract].” J Clin Oncol 26: 2008 (May 20 suppl; abstr 9019): Poster Discussion. Link to Abstract.

Min CJ, Liebes L, Escalon J, Hamilton A, Yee H, Buckley M, Wright J, Osman I, Polsky D, Pavlick A. Phase II trial of Sorafenib (S [BAY 43-9006]) in metastatic melanoma (MM) including detection of BRAF with mutant specific-PCR (MS-PCR) and altered proliferation pathways-final outcome analysis. J Clin Oncol 26: 2008 (May 20 suppl; abstr 9072): General Poster Session. Link to abstract.

Bogunovic D*, O'Neill D*, Adams S, Wang J, Darvishian F, Pavlick A, Shapiro R, Zavadil J, Osman I, Bhardwaj N.; * shared first authorship. “Gene expression profile for metastatic melanoma associated with prolonged patient survival [Abstract].” J Clin Oncol. 26: 2008 (May 20 suppl; abstr 9049). Link to abstract.

Firoz EF, Warycha M, Shapiro R, Berman R, Kamino H, Darvishian F, Rolnitzky L, J Goldberg L, Osman I, Polsky D. “MDM2 SNP309 and melanoma risk among women [Abstract].” J Clin Oncol. 26: 2008 (May 20 suppl; abstr 11099): General Poster Session. Link to abstract.

Warycha MA, Yu JZ, Christos P, Darvishian F, Kamino H, Shapiro R, Berman R, Kopf AW, Polsky D, and Osman I. Different clinical behavior of nodular melanoma (NM) compared to superficial spreading melanoma (SSM) at New York University from 1972 to present. J Clin Oncol 26: 2008 (May 20 suppl; abstr 20001). Link to abstract.

Zakrzewski J, Warycha MA, Ni Q, Shapiro R, Berman R, Pavlick A, Polsky D, Mazumda M, and Osman I. Meta-Analysis of Sentinel Lymph Node Positivity in Thin Melanoma (≤ 1mm). J Clin Oncol. 26: 2008 (May 20 suppl; abstr 20032). Link to abstract.

Velazquez EF, Jungbluth AA, Yancovitz M, Gnjatic S, Adams S, O'Neill D, Zavilevich K, Albukh T, Christos P, Mazumdar M, Pavlick A, Polsky D, Shapiro R, Berman R, Spira J, Busam K, Osman I, Bhardwaj N. Expression of the cancer/testis antigen NY-ESO-1 in primary and metastatic malignant melanoma (MM) - correlation with prognostic factors. Cancer Immun. 2007 Jul 12;7:11. PMID: 17625806

Yancovitz M, Finelt N, Warycha M, Christos P, Mazumdar M, Shapiro R, Pavlick A, Osman I, Polsky D, Berman R. Role of Radiologic Imaging at Time of Initial Diagnosis of Stage T1b-T3b Melanoma. Cancer. 2007; Jul 9;110(5):1107-1114. (PMID: 17620286 )

O'Neill DW, Bhardwaj N. Exploiting dendritic cells for active immunotherapy of cancer and chronic infections. Mol Biotechnol. 2007; Jun;36(2):131-41. (PMID: 17914192)

Manga P, Evers L, Perez B, Osman I, Orlow.SJ. “A Role for the Oculocutaneous Albinism Type 2 gene in determination of melanoma susceptibility [Abstract E-06]”. 2007 Proceedings International Melanoma Congress. Pigment Cell Res. 20; 513–580. Link to abstract.

Han SY, Warycha MA, Yancovitz M, Yoon J, Gai G, Chiriboga L, Wadsworth E, Kopf AW, Osman I, Polsky D. Assessing the Impact of BRAF mutation in ERK activation and cell proliferation in primary melanoma [Abstract]. 2007 Proceedings International Melanoma Congress, New York, NY (November 30-June 3; Abstr M-10). Link to abstract.

Yu JZ, Warycha M, Zakrzewski J, Yee H, Christos P, Berman R, Pavlick A, Shapiro R, Kamino H, Liebes L, Brooks P, and Osman I. “Differential expression of Insulin-like Growth Factor Binding Protein-4 (IGFBP-4) and Integrin avb3 in melanoma progression [Abstract].” 2007 Proceedings International Melanoma Congress, New York, NY (November 30-June 3; Abstr M-23). Link to abstract.

Yancovitz M, Yoon J, Warycha M, Zakrzewski JA, Spira J, Yu JZ, Gai W, Shapiro RL, Berman RS, Pavlick AC, Meehan S, Kamino H, Darvishian F, Osman I, Polsky D. “Detection of BRAF mutations in plasma and tissues of patients with metastatic melanoma [Abstract].” 2007 Proceedings International Melanoma Congress, New York, NY (November 30-June 3; Abstr M-25). Link to abstract.

Friedman K, Spira J, Pavlick A, Shapiro R, Berman R, and Osman I. “3D rendered PET/CT for preoperative assessment of locally recurrent melanoma [Abstract].” 2007 Proceedings International Melanoma Congress, New York, NY (November 30-June 3; Abstr T-30). Link to abstract.

Bhardwaj N. Harnessing the immune system to treat cancer. J Clin Invest. 2007 May. 117(5):1130-6. (PMID: 17476342)

Valmori D, Souleimanian NE, Tosello V, Bhardwaj N, Adams S, O'Neill D, Pavlick A, Escalon JB, Cruz CM, Angiulli A, Angiulli F, Mears G, Vogel SM, Pan L, Jungbluth AA, Hoffmann EW, Venhaus R, Ritter G, Old LJ, Ayyoub M. Vaccination with NY-ESO-1 protein and CpG in Montanide induces integrated antibody/Th1 responses and CD8 T cells through cross-priming. Proc Natl Acad Sci U S A. 2007 May 22.104(21):8947-52. Epub 2007 May 15. (PMID: 17517626 )

Yancovitz M, Yoon J, Mikhail M, Gai W, Shapiro R, Berman R, Pavlick A, Osman I, Polsky D. Detection of mutant BRAF alleles in the plasma of patients with metastatic melanoma. Journal of Molecular Diagnostics. 2007 Apr;9(2):178-83. (PMID: 17384209)

Velazquez EF, Yancovitz M, Pavlick A, Berman R, Shapiro R, Bogunovic D, O’Neill D, Yu YL, Spira J, Christos PJ, Zhou XK, Mazumdar M, Nanus DM, Liebes L, Bhardwaj N, Polsky D, and Osman I. Clinical relevance of Neutral Endopeptidase (NEP/CD10) in melanoma. J Transl Med. 2007 Jan 5; 5:2. (PMID: 17207277)

Millward MJ, Bedikian AY, Conry RM, Gore ME, Pehamberger HE, Sterry W, Pavlick AC, De Conti RC, Gordon D, Itri LM. “Randomized multinational Phase 3 trial of dacarbazine (DTIC) with or without Bcl-2 antisense (oblimersen sodium) in patients (pts) with advanced malignant melanoma (mm): Analysis of long-term survival [Abstract].” Journal of Clinical Oncology, 2004 ASCO Annual Meeting Proceedings (Post-Meeting Edition). Journal of clinical oncology. 2004; 22: 711S. (Link to abstract)

Freedberg DE, Mistry SH, Russak J, Gai W, Kaplow M, Osman I, Turner F, Randerson-Moor JA, Houghton A, Busam K, Bishop DT, Bastian BC, Newton-Bishop JA, Polsky D. Frequent genetic and epigenetic alteration of p14ARF in human melanoma. Under revision Nature Genetics.

Abassi NR, Gutkowicz-Krusin D, Panageas KS, Mihm MC, Osman I, Friedman RJ, Rigel DS, Kopf AW, Polsky D. Relevance of Lesion Diameter in Skin Biopsies to Diagnose Melanoma (Submitted – The Lancet)

Ni-Komatsu L, Leung JK, Williams D, Min J, Khersonsky SM, Chang YT, Orlow SJ. Triazine-based tyrosinase inhibitors identified by chemical genetic screening. Pigment Cell Res. 2005. Dec;18(6):447-53. PMID: 16280010.

Solit DB, Garraway LA, Pratilas C, Sawai A, Getz GA, Basso A, Ye Q, Lobo J, She Y, Osman I, Golub T, Sebolt-Leopold J, Sellers W, Rosen N. B-Raf mutation predicts sensitivity to MEK inhibition. Nature. 2006 Jan 19;439(7074):274-5. PMID: 16273091.

Ni-Komatsu L, Orlow SJ. Heterologous expression of tyrosinase recapitulates the misprocessing and mistrafficking in oculocutaneous albinism type 2: effects of altering intracellular pH and pink-eyed dilution gene expression. Exp Eye Res. 2006. Mar; 82(3):519-28. Epub 2005 Sep 30. PMID: 16199032

Mikhail M, Velazquez E, Shapiro R, Berman R, Pavlick A, Sorhaindo L, Spira J, Mer C, Panagias K, Polsky D and Osman I. PTEN Expression in Melanoma: Relationship in Patient Survival, Bcl-2 Expression and Proliferation. Clin Cancer Res. 2005 July 15; 11(4); 5153-7. PMID: 16033830

Schaffer JV, Orlow SJ. Melanocytic proliferations in the setting of vulvar lichen sclerosus: diagnostic considerations. Pediatr Dermatol. 2005 May-Jun; 22(3):276-8. PMID: 15916584

Hall AM, Orlow SJ. Degradation of tyrosinase induced by phenylthiourea occurs following Golgi maturation. Pigment Cell Res. 2005 Apr; 18(2):122-9. PMID: 15760341

Snyder JR, Hall A, Ni-Komatsu L, Khersonsky SM, Chang YT, Orlow SJ. Dissection of melanogenesis with small molecules identifies prohibitin as a regulator. Chem Biol. 2005 Apr; 12(4):477-84. PMID: 15850985

Finger PT, Kurli M, Reddy S, Tena LB, Pavlick AC. Whole body PET/CT for initial staging of choroidal melanoma. Br J Ophthalmol. 2005 Oct; 89(10):1270-4. PMID: 16170114

Adams S, O’Neill D, Bhardwaj N. Recent advances in dendritic cell biology. J Clin Immunol. 2005 May;25(3):177-88. PMID: 16118915

Hale E, Stein J, Ben-Porat L, Panageas KS, Eichenbaum MS, Marghoob AA, Osman I, Kopf AW, Polsky D. Association of Melanoma and Neurocutaneous Melanocytosis with Large Congenital Melanocytic Nevi – Results from the NYU-LCMN Registry. Br J Dermatol. 2005 Mar; 152 (3): 512-7. PMID: 15787820

Celebi JT, Ward KM, Wanner M, Polsky D, Kopf AW. Evaluation of Germline CDKN2A, ARF, CDK4, PTEN, and BRAF Alterations in Atypical Mole Syndrome. Clin Exp Dermatol. 2005 Jan;30(1):68-70. PMID: 15663508

** Hamilton AL, Eder JP, Pavlick AC, Clark JW, Liebes L, Garcia-Carbonero R, Chachoua A, Ryan DP, Soma V, Farrell K, Kinchla N, Boyden J, Yee H, Zeleniuch-Jacquotte A, Wright J, Elliott P, Adams J, Muggia FM. Proteasome inhibition with bortezomib (PS-341): A Phase I study with pharmacodynamic end points using a day 1 and day 4 schedule in a 14-day cycle. J Clin Oncol. 2005; 23 (25):6107-16. PMID: 16135477

Kurli M, Reddy S, Tena LB, Pavlick AC, Finger PT. Whole body positron emission tomography/computerized tomography staging of metastatic choroidal melanoma. Amer J Ophthalmol. 2005; 140: 193-9. PMID: 15992753

Jungbluth, A., Ely, S., Williamson,B., Chen, Y-T.,Bhardwaj, N., Chen Y-T, Bhardwaj, N., Chen-Kiang, S.,Old, L., and Cho, H. The Cancer-Testis, antigens CT7 (MAGE-C1) and MAGE-A3 are commonly expressed in multiple myeloma and correlate with plasma cell proliferation. Blood. 2005. 106: 167-174. PMID: 15761016

O’Neill D and Bhardwaj N. Exploiting Dendritic Cells for Active Immunotherapy of Cancer and Chronic Infections. Methods in Molecular Medicine. 2005; 109: 1-18. PMID: 15585909

O’Neill D and Bhardwaj N. Generation of autologous peptide-and protein-pulsed dendritic cells for patient-specific immunotherapy. Methods in Molecular Medicine. 2005; 109: 97-112. PMID: 15585916

Polsky D. The ABCDEs of melanoma: an evolving concept, J Drugs Dermatol 2005, 4:399-401. PMID: 15898299

Rigel DS, Friedman RJ, Kopf AW, Polsky D: ABCDE--an evolving concept in the early detection of melanoma, Arch Dermatol 2005, 141:1032-4. PMID: 16103334

Skoberne M, Beignon AS, Larsson M, Bhardwaj N. Apoptotic cells at the crossroads of tolerance and immunity. : Curr Top Microbiol Immunol. 2005;289:259-92. PMID: 15791960

Chang DZ, Panageas KS, Osman I, Polsky D, Busam K, Chapman PB. Clinical Significance of BRAF Mutations in Metastatic Melanoma. J Transl Med. 2004 Dec 21; 2 (1): 46. PMID: 15613230

Staleva L, Hall A, Orlow SJ. Oxidative stress activates FUS1 and RLM1 transcription in the yeast Saccharomyces cerevisiae in an oxidant-dependent Manner. Mol Biol Cell. 2004 Dec;15(12):5574-82. PMID: 15385622

Abassi NR, Shaw HM, Rigel DS, Friedman RJ, McCarthy WH, Osman I, Kopf AW, Polsky D. Early Diagnosis of Cutaneous Melanoma: Revisiting the ABCD Criteria. JAMA. 2004 Dec 8; 292 (22): 2771-6. PMID: 15585738

Chiriboga L, Osman I, Mikhail M, Lau C. Tissue microarrays, tread carefully. Lab Invest. 2004 Dec; 84 (12):1677. PMID: 15545964

Beermann F, Orlow SJ, Lamoreux ML. The Tyr (albino) locus of the laboratory mouse. Mamm Genome. 2004 Oct; 15(10):749-58. PMID: 15520878

Williams D, Jung DW, Khersonsky SM, Heidary N, Chang YT, Orlow SJ. Identification of compounds that bind mitochondrial F1F0 ATPase by screening a triazine library for correction of albinism. Chem Biol. 2004 Sep; 11(9):1251-9. PMID: 15380185

Hall AM, Krishnamoorthy L, Orlow SJ. 25-hydroxycholesterol acts in the Golgi compartment to induce degradation of tyrosinase. Pigment Cell Res. 2004 Aug; 17(4):396-406. PMID: 15250942

Pavlick A, and Bailes A. “Overview of Malignant Melanoma”, 2004 Educational Review Manual in Medical Oncology. 2004 May.

Chen K, Minwalla L, Ni L, Orlow SJ. Correction of defective early tyrosinase processing by bafilomycin A1 and monensin in pink-eyed dilution melanocytes. Pigment Cell Res. 2004 Feb;17(1):36-42. PMID: 14717843

Wang SQ, Kopf AW, Koenig K, Polsky D, Nudel K, Bart RS. Detection of melanomas in patients followed up with total cutaneous examinations, total cutaneous photography, and dermoscopy. J Am Acad Dermatol. 2004 Jan; 50(1):15-20. PMID: 14699359

Adams S, O’Neill D, Bhardwaj N. Maturation matters: Importance of maturation for anti-tumor immunity of dendritic cell vaccines. J. Of Clinical Oncology. 22 (18) 3834-5, 2004.

Finger PT, Kurli M, Wesley P, Tena L, Kerr KR, Pavlick A. Whole body PET/CT imaging for detection of metastatic choroidal melanoma. Br J Ophthalmol. 2004; 88(8):1095-7. PMID: 15258035

Friedman K, Wahl RL: Clinical use of positron emission tomography in the management of cutaneous melanoma. Semin Nucl Med 2004;34(4)242-53. PMID: 15493002

Friedman KP, Whitaker-Worth DL, Grin C, Grant-Kels JM. Melanoma screening behavior among primary care physicians. Cutis 2004;74(5)305-11. PMID: 15605968

O’Neill D, Adams S, Bhardwaj N. Manipulating dendritic cell biology for the active immunotherapy of cancer. Blood. 2004 Vol. 104 (8): 2235-46. PMID: 15231572

** Pavlick AC, Chodkiewicz C, Liebes L, Hamilton A, Wasserheit C, Hochster H, Speyer J, Phillips Z, Downey A, Sorich J, and Muggia F. A Phase I and pharmacokinetic study of docetaxel combined with Doxil (pegylated liposomal doxorubicin) without and with granulocyte colony stimulating factor. Anti-Cancer Drugs. 2004; 15(2):119-125. PMID: 15075667

Skoberne,M.,Beignon, A.S., and Bhardwaj, N. Danger Signals: a time and space continuum. Trends in Molecular Medicine. Vol. 10:6, 2004. PMID: 15177188

Gorden A, Osman I, Gai W, He D, Huang W, Davidson A, Houghton AN, Busam K, Polsky D. Analysis of BRAF and N-RAS Mutations in Metastatic Melanoma Tissues. Cancer Res. 2003 Jul 15; 63(14):3955-7. PMID: 12873990

Beignon, A.S., Skoberne M., Bhardwaj N. Type I interferons promote cross-priming: more functions for old cytokines. Nature Immunology. 4:10, 939-941, 2003. PMID: 14515123

Cho, H., Bhardwaj, N. Against the self: dendritic cells versus cancer. APMIS; 112:000-000, 2003. PMID: 12974782

Fonteneau, J-F., Kavanagh, D, Lirvall, M, Sanders,C Cover, T., Bhardwaj, N., and Larsson, M. Characterization of the MHC class I crosspresentation pathway for cell associated antigens by human dendritic cells. Blood; 102; 4448-4454, 2003. PMID: 12933572

** Haigentz M Jr, Kim M, Sorich J, Lee J, Hochster H, Macapinlac M, Mirchandani D, Sewak S, Pavlick A, Volm M, Hamilton A, Muggia FM. Phase I study of amifostine as a cytoprotector of the gemcitabine/cisplatin combination in patients with advanced solid malignancies. Anticancer Drugs. 2003; 14(4):321-6. PMID: 12679737

Pavlick A. “Chemotherapy Approaches to Malignant Melanoma”, Dermatology Clinics of North America, 2003.

Pavlick AC, Adams S, Fink MA, Bailes A. Novel therapeutic agents under investigation for malignant melanoma. Expert Opin Investig Drugs. 2003; 12(9):1545-58. PMID: 12943498

Staleva L, Manga P, Orlow SJ. Pink-eyed dilution protein modulates arsenic sensitivity and intracellular glutathione metabolism. Mol Biol Cell. 2002 Dec;13(12):4206-20. PMID: 12475946

Polsky D, Melzer K, Hazan C, Panageas KS, Busam K, Kamino K, Spira J, Kopf A, Houghton A, Cordon-Cardo C, Osman I. HDM2 Protein Overexpression Correlates with Favorable Prognosis in Primary Malignant Melanoma. J Natl Cancer Inst. 2002 Dec 4; 94(23):1803-6.

Houghton AN, Polsky D. Focus on melanoma. Cancer Cell 2002 Oct;2(4):275-8. PMID: 12398891
Zaenglein AL, Heintz P, Kamino H, Zisblatt M, Orlow SJ. Congenital Spitz nevus clinically mimicking melanoma. J Am Acad Dermatol. 2002 Sep; 47(3):441-4. PMID: 12196758

Hazan C, Melzer K, Panageas K, Li E, Kamino H, Kopf A, Cordon-Cardo C, Osman I, Polsky D. Evaluation of Ki67 Proliferative Index as a Prognostic Marker in Cutaneous Malignant Melanoma. Cancer. 2002 Aug 1; 95(3): 634-40.

Chen K, Manga P, Orlow SJ. Pink-eyed dilution protein controls the processing of tyrosinase. Mol Biol Cell. 2002 Jun;13(6):1953-64. PMID: 12058062

Chen Y, Samaraweera P, Sun TT, Kreibich G, Orlow SJ. Rab27b association with melanosomes: dominant negative mutants disrupt melanosomal movement. J Invest Dermatol. 2002 Jun; 118(6):933-40. PMID: 12060386

Sviderskaya EV, Hill SP, Evans-Whipp TJ, Chin L, Orlow SJ, Easty DJ, Cheong SC, Beach D, DePinho RA, Bennett DC. p16(Ink4a) in melanocyte senescence and differentiation. J Natl Cancer Inst. 2002 Mar 20;94(6):446-54. Erratum in: J Natl Cancer Inst. 2002 Jun 5;94(11):866. PMID: 11904317

Pavlick A, and Bailes A. “Overview of Malignant Melanoma”, 2002 Educational Review Manual in Medical Oncology. May 2002.

Pavlick AC. Chemotherapy approaches to melanoma. Dermatol Clin. 2002; 20(4):709-12. PMID: 12380057

Shen B, Orlow SJ. The ocular albinism type 1 gene product is an N-glycoprotein but glycosylation is not required for its subcellular distribution. Pigment Cell Res. Dec; 14(6):485-90, 2001. Link to reference.

Schaffer JV, Orlow SJ, Lazova R, Bolognia JL. Speckled lentiginous nevus--classic congenital melanocytic nevus hybrid not the result of "collision". Arch Dermatol. Dec; 137(12):1655, 2001. Link to article.

Polsky D, Bastian B, Hazan C, Melzer K, Pack J, Houghton A, Busam K, Cordon- Cardo C, Osman I. HDM2 protein expression but not gene amplification, is related to tumorigenis of melanoma. Cancer Res. Oct 15; 61:7642-6. 2001. PMID: 12464652

Manga P, Orlow SJ. Inverse correlation between pink-eyed dilution protein expression and induction of melanogenesis by bafilomycin A1. Pigment Cell Res. Oct; 14(5):362-7, 2001. PMID: 11601658

Shen B, Samaraweera P, Rosenberg B, Orlow SJ. Ocular albinism type 1: more than meets the eye. Pigment Cell Res. Aug; 14(4):243-8. 2001. PMID: 11549106

Manga P, Boissy RE, Pifko-Hirst S, Zhou BK, Orlow SJ. Mislocalization of melanosomal proteins in melanocytes from mice with oculocutaneous albinism type 2. Exp Eye Res. Jun; 72(6):695-710, 2001. PMID: 11384158

Larsson, M., Fonteneau, J.F., Bhardwaj, N. Dendritic cells resurrect antigens from dead cells. Trends Immunol. Mar;22(3):141-8, 2001. PMID: 11286729

Samaraweera P, Shen B, Newton JM, Barsh GS, Orlow SJ. The mouse ocular albinism 1 gene product is an endolysosomal protein. Exp Eye Res. Mar; 72(3):319-29, 2001. PMID: 11180981

Shen B, Rosenberg B, Orlow SJ. Intracellular distribution and late endosomal effects of the ocular albinism type 1 gene product: consequences of disease-causing mutations and implications for melanosome biogenesis. Traffic. Mar;2(3):202-11. 2001 PMID: 11260525

Schaffer JV, Orlow SJ, Lazova R, Bolognia JL. Speckled lentiginous nevus: within the spectrum of congenital melanocytic nevi. Arch Dermatol. Feb; 137(2):172-8. 2001. PMID: 11176689

Banchereau, J., Palucka, A. K., Dhodapkar, M., Burkeholder, S., Taquet, N., Rolland, A., Taquet, S., Coquery, S., Wittkowski, K., Bhardwaj, N., Pineiro, L., Steinman, R. M., Fay, J. Immune and clinical responses after vaccination of patients with metastatic melanoma with CD34+ hematopoietic progenitor-derived dendritic cells. Cancer Research. 61:6451-6458, 2001. Link to article.

Bhardwaj, N. The processing and presentation of antigens by dendritic cells: implications for vaccines. Trends in Molecular Medicine. 7:9:388-394, 2001. Link to article.

Dhodapkar, M.V., Steinman, R.M., Krasovsky, J., Munz, C., Bhardwaj, N. Antigen specific inhibition of effector cell function in humans after injection of immature dendritic cells. J. Exp. Med. 15:193:233-238, 2001. PMID: 11208863

Dhodapkar, M,V., young, J.W., Chapman, P.B., Cox, W.I., Fonteneau, J.F., Amigorena, S., Houghton, A., Steinman, R. M., Bhardwaj, N. Paucity of functional T cell memory to melanoma antigens in healthy donors and melanoma patients. Clin Cancer Res. 6: 4831-4838, 2001. PMID: 11156242

Fonteneau, J.F., Larsson, M., Bhardwaj, N. Dendritic cells – dead cells interactions: implications and relevance for immunotherapy. J. Immunotherapy 24:4:294-304, 2001. PMID: 11565831

Fonteneau, J.F., Larsson, M., Somersan, S., Sanders, C., Munz, C., Kwok, W.W., Bhardwaj, N., Jotereau, J. Generation of high quantities of viral and tumor specific human CD4+ and CD8+ T cell clones using peptide pulsed mature dendritic cells. J. Immunol. Methods. 258:111-126, 2001. PMID: 11684128

Polsky D, Young AZ, Busam KJ, Alani RM. The transcriptional repressor of p16/Ink4a, Id1, is up-regulated in early melanomas. Cancer Res. 61(16):6008-11, 2001. PMID: 11507043

Soengas MS, Capodieci P, Polsky D, Mora J, Esteller M, Optiz-Araya X, McCombie R, Herman JG, Gerald WL, Lazebnik YA, Cordon-Cardo C, Lowe SW. Inactivation of the apoptosis effector Apaf-1 in melanoma. Nature. 409:207-11, 2001. PMID: 11196646

Somersan, S., Larsson, M., Fonteneau, J.F., Basu, S., Srivastava, Bhardwaj, N. Primary tumor tissue lysates are enriched in heat shock proteins and induce the maturation of human dendritic cells. J. Immunol. 2001. 167:4844-4852. PMID: 11673488

Wang SQ, Kopf AW, Marx J, Bogdan A, Polsky D, Bart RS. Reduction of ultraviolet transmission through cotton T-shirt fabrics with low ultraviolet protection by various laundering methods and dyeing: clinical implications. J Am Acad Dermatol. 2001. May; 44(5):767-74. PMID: 11312422

Wang SQ, Setlow R, Berwick M, Polsky D, Marghoob A, Kopf AW, Bart RS. Ultraviolet A and melanoma: a review. J Am Acad Dermatol. 2001. 44:837-46. PMID: 11312434