Prashiela Manga Ph.D.

Assistant Professor

Departments of Dermatology and Cell Biology

Education

Graduate Education
Univ of Witwaterand 1981-1997
PostDoctoral Training
NYU School of Medicine 1997-2002

Publications

• Bis, SG; Knoll, KE; Lolis, MS; Orlow, SJ; Manga, P. "Initiation of the unfolded protein response in melanocytes and melanoma [Abstract]". Journal of investigative dermatology. 2009; 129: S139 (#J0165318)
• Firoz, EF; Warycha, M; Zakrzewski, J; Pollens, D; Wang, G; Shapiro, R; Berman, R; Pavlick, A; Manga, P; Ostrer, H; Celebi, JT; Kamino, H; Darvishian, F; Rolnitzky, L; Goldberg, JD; Osman, I; Polsky, D. "Association of MDM2 SNO309, Age of Onset, and Gender in Cutaneous Melanoma". Clinical cancer research. 2009; 15: 2573 (#J0165388)
• Manga P; Goldberg JD; Belitskaya-Levy I; Lobach I; Polsky D; Pavlick A; Shapiro R; Berman R; Osman I; Ostrer H. "Developing genetic markers for melanoma risk assessment [Abstract]". Journal of clinical oncology. 2009; 27: 15S (#J0176403)
• Sidash S; Ostrer H; Goldberg JD; Belitskaya-Levy I; Lobach I; Polsky D; Shapiro RL; Berman RS; Osman I; Manga P. "Evaluation of the melanocortin-1-receptor gene in melanoma predisposition, progression and recurrence [Abstract]". Journal of clinical oncology. 2009; 27: 15S (#J0176404)
• Wich L.G.; Hamilton H.K.; Shapiro R.L.; Pavlick A.; Berman R.S.; Polsky D.; Goldberg J.D.; Hernando E.; Manga P.; Krogsgaard M.; Kamino H.; Darvishian F.; Lee P.; Orlow S.J.; Oster H.; Bhardwaj N.; Osman I.. "Developing a multidisciplinary prospective melanoma biospecimen repository to advance translational research". American Journal of Translational Research. 2009; 1: 35 (#J0175687)
• Bowling, Benjamin D; Doudican, Nicole; Manga, Prashiela; Orlow, Seth J. "Inhibition of mitochondrial protein translation sensitizes melanoma cells to arsenic trioxide cytotoxicity via a reactive oxygen species dependent mechanism". Cancer chemotherapy & pharmacology. 2008; 63: 37 (#J0156839)
• Manga, P; Knoll, K; Fenton, J; Orlow, SJ. "A role for the pink-eyed dilution protein in tyrosinase folding [Abstract]". Pigment cell & melanoma research. 2008; 21: 261 (#J0137567)
• Epstein, H; Manga, P; Koshoffer, A; Story, D; Simion, T; Boissy, R. "Does melanin have an SPF and can it be measured?". Journal of cosmetic science. 2007; 58: 596 (#J0150857)
• Manga, Prashiela; Sheyn, David; Yang, Fan; Sarangarajan, Rangaprasad; Boissy, Raymond E. "A Role for Tyrosinase-Related Protein 1 in 4-tert-Butylphenol-Induced Toxicity in Melanocytes: Implications for Vitiligo". American journal of pathology. 2006; 169: 1652 (#J0121414)
• Boissy, Raymond E; Manga, Prashiela. "On the etiology of contact/occupational vitiligo". Pigment cell research. 2004; 17: 208 (#J0121016)
• Chen K; Manga P; Orlow SJ. "Pink-eyed dilution protein controls the processing of tyrosinase". Molecular biology of the cell. 2002; 13: 1953 (#J0047967)
• Staleva L; Manga P; Orlow SJ. "Pink-eyed Dilution Protein Modulates Arsenic Sensitivity and Intracellular Glutathione Metabolism". Molecular biology of the cell. 2002; 13: 4206 (#J0047964)
• Chen, K; Manga, P; Orlow, S. "Abnormal tyrosinase processing and fate in melanocytes lacking the pink-eyed dilution gene [Abstract]". Journal of investigative dermatology. 2001; 117: 510 (#J0099322)
• Manga P; Orlow SJ. "Inverse correlation between pink-eyed dilution protein expression and induction of melanogenesis by bafilomycin A1". Pigment cell research. 2001; 14: 362 (#J0047971)
• Manga P; Boissy RE; Pifko-Hirst S; Zhou BK; Orlow SJ. "Mislocalization of melanosomal proteins in melanocytes from mice with oculocutaneous albinism type 2". Experimental eye research. 2001; 72: 695 (#J0023145)
• Manga P; Sato K; Ye L; Beermann F; Lamoreux ML; Orlow SJ. "Mutational analysis of the modulation of tyrosinase by tyrosinase-related proteins 1 and 2 in vitro". Pigment cell research. 2000; 13: 364 (#J0047977)
• Manga P; Orlow SJ. "The pink-eyed dilution gene and the molecular pathogenesis of tyrosinase-positive albinism (OCA2)". Journal of dermatology. 1999; 26: 738 (#J0009179)

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