Clinical Trials

Disease

Chronic Plaque Psoriasis

Title

A comparison between the microbial flora of normal human skin and skin from patients with psoriasis and other inflammatory conditions using broad-range PCR

Inclusion*

Moderate to severe psoriasis patients who are not currently under treatment (baseline visit) and are eligible to receive either methotrexate or adalimumab (week 12 and 36 visit)

Study Contact

bryan.sofen@nyumc.org

Principal Investigator

Dr. Martin Blaser

Objective

To evaluate the cutaneous microbial flora.

No study agents will be administered in this study. All patients will receive standard of care treatments prescribed by the patient's physician.

Status

RECRUITING

Age Requirement

18-75 years of age

Gender

males and females

 

Disease

Pityriasis Rubra Pilaris

Title

A comparison between the microbial flora of normal human skin and skin from patients with psoriasis and other inflammatory conditions using broad-range PCR

Inclusion*

Pityriasis rubra pilaris patients who are not currently under treatment

Study Contact

bryan.sofen@nyumc.org

Principal Investigator

Dr. Martin Blaser

Objective

To evaluate the cutaneous microbial flora.

No study agents will be administered in this study. All patients will receive standard of care treatments prescribed by the patient's physician.

Status

RECRUITING

Age Requirement

18-75 years of age

Gender

males and females

 

 Disease

Chronic Plaque Psoriasis

Title

Phase 2a, randomized, double-blind, placebo-controlled study to assess the efficacy and safety of a new oral medication in subjects with moderate to severe psoriasis

Inclusion*

Stable moderate to severe chronic plaque psoriasis for at least 6 months

Study Contact

bryan.sofen@nyumc.org

Principal Investigator

Dr. Jerome Shupack

Objective

To evaluate the safety and efficacy of a new treatment

Status

RECRUITING

Age Requirement

18-80 years of age

Gender

males and females*

 

Disease

Chronic Plaque Psoriasis

Title

Multi-center, open registry of patients with psoriasis who are candidates for systemic therapies including biologics

Inclusion*

Patients with all forms of psoriasis receiving systemic therapy

Study Contact

bryan.sofen@nyumc.org

Principal Investigator

Dr. Jerome Shupack

Objective

Registry study to evaluate the safety and efficacy of systemic treatments for psoriasis.

No study agents will be administered in this registry. All patients will receive standard of care treatments prescribed by the patient's physician.

Status

RECRUITING

Age Requirement

≥ 18 years of age

Gender

males and females

 

 Disease

Chronic Plaque Psoriasis

 Title

A phase 3, multi-site, randomized, double-blind, placebo-controlled, paralle-group study of the efficacy and safety of 2 doses of a new oral medication in subjects with moderate to severe chronic plaque psoriasis

 Inclusion*

 Stable moderate to severe chronic plaque psoriasis for at least 6 months

 Study Contact

 bryan.sofen@nyumc.org

 Principal investigator

 Dr. Jerome Shupack

 Objective

 To evaluate the safety and efficacy of a new treatment

 Status

 Recruitment will start soon

 Age Requirement

 ≥ 18 years of age

 Gender

 males and females*

 

 Disease

 

Chronic Plaque Psoriasis

 Title

A phase 3, multi-site, open-label study of the long term safety and tolerability of 2 oral doses of a new medication in subjects with moderate to severe chronic plaque psoriasis

 Inclusion*

 Participation in the above mentioned study

 Study Contact

 bryan.sofen@nyumc.org

 Principal Investigator

 Dr. Jerome Shupack

 Objective

 To evaluate the long term safety and efficacy of a new treatment

 Status

 Recruitment will start soon

 Age Requirement

 ≥ 18 years of age

 Gender

 males and females*

 

Disease

Discoid and Subacute Cutaneous Lupus Erythematosus

Title

Phase 2, pilot, multicenter, ascending dose study to evaluate the preliminary safety and efficacy of a new oral medication to treat discoid lupus erythematosus and subacute cutaneous lupus erythematosus

Inclusion*

Men and women, who are 18 years of age or older with a biopsy-proven diagnosis of cutaneous discoid lupus. No evidence of systemic lupus (involvement of internal organs and/or inflammation of blood vessels or joints).

Study Contact

bryan.sofen@nyumc.org

Principal Investigator

Dr. Andrew G. Franks

Objective

To evaluate the clinical response of discoid lupus patients to an investigational oral medication

Status

RECRUITING

Age Requirement

≥ 18 years of age

Gender

males and females*

 

*: Required for all studies: females of childbearing age must have a negative pregnancy test at screening and agree to use at least two forms of contraception during their participation in the study.

For complete information regarding inclusion and exclusion criteria, please call 212-263-6881 or email bryan.sofen@nyumc.org